CXCL16 antibody

CXCL16 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CXCL16 Mouse Monoclonal antibody. Positive WB detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 35 kDa, 60 kDa

ELISA, WB

Human, Mouse; other species not tested.

C X C motif chemokine 16 antibody; CXCL16 antibody; CXCLG16 antibody; SCYB16 antibody; Small inducible cytokine B16 antibody; SR PSOX antibody; SRPSOX antibody; Transmembrane chemokine CXCL16 antibody

Mouse IgG2a

This antibody was obtained by immunization of CXCL16 recombinant protein (Accession Number: NM_022059). Purification method: Caprylic acid/ammonium sulfate precipitation.

Monoclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.