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  • CXCL16 antibody

CXCL16 antibody

Cat.#: 107184

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Special Price 239.0 USD

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Product Information

  • Product Name
    CXCL16 antibody
  • Documents
  • Description
    CXCL16 Mouse Monoclonal antibody. Positive WB detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 35 kDa, 60 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    C X C motif chemokine 16 antibody; CXCL16 antibody; CXCLG16 antibody; SCYB16 antibody; Small inducible cytokine B16 antibody; SR PSOX antibody; SRPSOX antibody; Transmembrane chemokine CXCL16 antibody
  • Immunogen
  • Isotype
    Mouse IgG2a
  • Preparation
    This antibody was obtained by immunization of CXCL16 recombinant protein (Accession Number: BC017588). Purification method: Caprylic acid/ammonium sulfate precipitation.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:107184(CXCL16 antibody) at dilution of 1:300

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:107184(CXCL16 antibody) at dilution of 1:300

  • Background
    CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"