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Product Name
Human Coagulation Factor VII (His Tag) recombinant protein
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Description
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
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Protein name
Coagulation factor VII
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Protein short names
FVII; COAGULATION FACTOR VII; MFVII; AI132620; CF7; SPCA; F7
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Uniprot ID
P08709
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Gene Name
F7
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human F7 isoform B (P08709-2) (Met 1-Pro 444) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted mature form of recombinant human F7 consists of 417 amino acids and predictes a molecular mass of 46.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh F7 is approximately 50 kDa.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human Coagulation Factor VII / FVII / F7 Protein (His Tag) SDS-PAGE
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"