CHOP; GADD153 antibody

CHOP; GADD153 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CHOP; GADD153 Mouse Monoclonal antibody. Positive WB detected in Tunicamycin treated HeLa cells. Observed molecular weight by Western-blot: 30 kDa

ELISA, WB

Human; other species not tested.

C/EBP homologous protein antibody; C/EBP homologous protein 10 antibody; CEBPZ antibody; CHOP antibody; CHOP 10 antibody; CHOP; GADD153 antibody; CHOP10 antibody; DDIT 3 antibody; DDIT3 antibody; GADD153 antibody

Mouse IgG2a

This antibody was obtained by immunization of CHOP; GADD153 recombinant protein (Accession Number: NM_004083). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.