Human CDC42 (GST Tag) recombinant protein

Cat.#: 501214

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Product Information

  • Product Name
    Human CDC42 (GST Tag) recombinant protein
  • Documents
  • Description
    Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
  • Protein name
    Cell division control protein 42 homolog
  • Protein short names
    RP23-246F18.2; AU018915; RP1-224A6.5; G25K; CDC42HS; AI747189; CDC42
  • Uniprot ID
    P60953
  • Gene Name
    CDC42
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human CDC42 isoform 2 (P60953-2) (Met 1-Cys 188) was fused with the GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CDC42/GST chimera consists of 423 amino acids and has a predicted molecular mass of 48.1 kDa. It migrates as an approxiamtely 44 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Validations

    Human CDC42 / G25K Protein (GST Tag) SDS-PAGE

    Human CDC42 / G25K Protein (GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"