NovoPro
Cart 2
  • Anti-CDC42 Rabbit antibody

Anti-CDC42 Rabbit antibody

Cat.#: 168973

Size:

Special Price 441.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-CDC42 Rabbit antibody
  • Documents
  • Description
    CDC42 Rabbit monoclonal antibody
  • Tested applications
    FC, ICC/IF, WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    TKS; G25K; CDC42Hs antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human CDC42
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/2000-1/10000

    WB: 1/2000-1/10000

    IHC: 1/20

    ICC/IF: 1/20

    FC: 1/50

    IP: 1/20

  • Validations

    Western blot detection of CDC42 in C6,Hela cell lysates using CDC42 Rabbit mAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:21kDa.

    Western blot detection of CDC42 in C6,Hela cell lysates using CDC42 Rabbit mAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:21kDa.

  • Background
    Swiss-Prot Acc.P60953.Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation . Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"