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Product Name
Mouse CD63 / Tspan-30 / Tetraspanin-30 (Fc Tag) recombinant protein
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Description
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
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Protein name
CD63 antigen
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Protein short names
CD63; MGC103180; ME491; TSPAN30; C75951; OMA81H; LAMP-3; MLA1; MGC107286
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Uniprot ID
Q549D0
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Gene Name
Cd63
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Cd63 (NP_031679.1) (Ala103-Ile203) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Cd63 consists 361 amino acids and predicts a molecular mass of 39.9 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse CD63 / Tspan-30 / Tetraspanin-30 Protein (Fc Tag)
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