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Product Name
Rat CD34 (Fc Tag) recombinant protein
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Description
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. It has been widely used as a stem and progenitor cell marker, and clinical CD34+ stem cell transplantation (CD34+SCT) has been performed for tumor purging. CD34 monoclonal antibodies are widely used to identify and isolate hemopoietic progenitors and to classify acute and chronic leukemias.
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Protein name
CD34 antigen (Predicted)
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Protein short names
AU040960; RP11-328D5.2; CD34
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Uniprot ID
B1PLB1
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Gene Name
Cd34; Cd34_predicted; LOC100911324; rCG_20068
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat CD34 (B1PLB1) (Met1-Thr291) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat CD34/Fc is a disulfide-linked homodimer. The reduced monomer comprises 496 amino acids and has a predicted molecular mass of 54.5 kDa. The apparent molecular mass of the protein is approximately 112 kDa in SDS-PAGE under reducing conditions.
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Purity
> 80 % as determined by SDS-PAGE
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Validations
Rat CD34 Protein (Fc Tag) SDS-PAGE
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