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Product Name
Mouse CD180/RP105 (Fc Tag) recombinant protein
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Description
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
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Protein name
CD180 antigen
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Protein short names
F630107B15; MGC126234; MGC126233; RP105; LY78; LY64; CD180
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Uniprot ID
Q62192
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Gene Name
Cd180; Ly78; Rp105
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CD180 (NP_032559.2) extracellular domain (Met 1-Ser 626) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse CD180/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 847 amino acids and predicts a molecular mass of 95 kDa. As a result of glycosylation, the apparent molecular mass of rm CD180/Fc monomer is approximately 110 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Mouse CD180 / RP105 Protein (Fc Tag) SDS-PAGE
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