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Product Name
Human CSNK1A1/CKI alpha (GST Tag) recombinant protein
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Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
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Protein name
Casein kinase I isoform alpha
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Protein short names
MGC29354; CSNK1A1; CK1; 4632404G05RIK; HEL-S-77P; CKI-ALPHA; 5430427P18RIK; HLCDGP1; CK1A; CKIA; 2610208K14RIK; PRO2975; CSNK1A; MGC30571
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Uniprot ID
P48729
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Gene Name
CSNK1A1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of human CSNK1A1 isoform 1 (P48729-1) (Met 1-Phe 337) was expressed with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CSNK1A1/GST chimera consists of 561 amino acids and predicts a molecular mass of 65.2 kDa. It migrates as an approximately 62 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
The specific activity was determined to be 30 nmol/min/mg using casein as substrate.
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Validations
Human CSNK1A1 / CKI-alpha / CK1 Protein (GST Tag) SDS-PAGE
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