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Human Calsequestrin-1 / CASQ1 recombinant protein

Cat.#: 502119

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Product Information

  • Product Name
    Human Calsequestrin-1 / CASQ1 recombinant protein
  • Documents
  • Description
    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.
  • Protein name
    Calsequestrin-1
  • Protein short names
    CASQ; SKELETAL MUSCLE ISOFORM; SKELETAL MUSCLE ISOFORM; CALSEQUESTRIN-1; CASQ1; VMCQA; CALSEQUESTRIN; CALMITINE; CSQ-1; PDIB1; CALSEQUESTRIN 1 (FAST-TWITCH; CALMITIN; CALSEQUESTRIN 1; CSQ1; SCSQ; RP11-536C5.6; SKELETAL MUSCLE); CSQ
  • Uniprot ID
    P31415
  • Gene Name
    CASQ1; CASQ
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human CASQ1 (P31415) (Gln35-Asp396) was expressed with a N-terminal Met.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CASQ1 consists of 363 amino acids and predicts a molecular mass of 41.8 KDa. It migrates as an approximately 52 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human Calsequestrin-1 / CASQ1 Protein SDS-PAGE

    Human Calsequestrin-1 / CASQ1 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"