C3 / C3b / C3c antibody

C3 / C3b / C3c antibody

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C3 / C3b / C3c Mouse Monoclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in human blood tissue. Observed molecular weight by Western-blot: 115 kDa

ELISA, WB, IHC

Human; other species not tested.

ARMD9 antibody; ASP antibody; C3b antibody; C3c antibody; Complement C3 antibody; complement component 3 antibody; CPAMD1 antibody

Mouse IgG1

This antibody was obtained by immunization of C3 / C3b / C3c recombinant protein (Accession Number: NM_000064). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

The complement system is an important effector which bridges the innate and adaptive immune systems (PMID: 20010915). The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways (PMID: 11414361). Human C3, composed of α and β chains (115 and 75 kDa, respectively), is cleaved into C3a and C3b by C3 convertase. C3b is further cleaved into iC3b, C3c, C3dg and C3f. This antibody raised against 1314-1663 aa of human C3 protein recognize C3 alpha chain, C3b alpha' chain, and C3c alpha' chain fragment 2.