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Product Name
Rhesus CCL21/6Ckine recombinant protein
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Description
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity).
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Protein name
C-C motif chemokine 21
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Protein short names
CCL21; SLC; CCL21A; RP11-195F19.22-001; ALP; AW987545; SCYA21B; RP23-411B7.4; SCYA21A; SCYA21; MGC34555; MGC107632; 6CKBAC2; CKB9; 6CKINE; ECL; TCA4
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Uniprot ID
Q8HYP5
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Gene Name
CCL21
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rhesus CCL21 (NP_001028027.1) (Met 1-Pro131) was expressed and purified.
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Protein Species
Rhesus
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Molecular weight
The recombinant rhesus CCL21 consists of 108 amino acids and has a calculated molecular mass of 12 kDa.
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Purity
> 94 % as determined by SDS-PAGE
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Validations
Cynomolgus CCL21 / 6Ckine Protein SDS-PAGE
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