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Product Name
Human CD147/EMMPRIN recombinant protein
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Description
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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Protein name
Basigin
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Protein short names
EMMPRIN; CD147; AI325119; 5F7; BSG; AI115436; HT-7; TCSF; OK; BASIGIN; M6
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Uniprot ID
Q54A51
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Gene Name
BSG; UNQ6505/PRO21383
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
The mature form of human CD147 (NP_940991.1) extracellular domain (Met 1-His 205) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified.
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Protein Species
Human
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Molecular weight
The recombinant mature human CD147 cytokine comprises 190 amino acids and has a predicted molecular mass of 20.7 kDa. As a result of glycosylation, the rhCD147 migrates as an approximately 35-38 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE and SEC-HPLC Analysis.
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Activity
Using the Octet RED System, the affinity constant (Kd) of human CD147 (Cat:500694) bound to Human PPIA-His (Cat:501254) was 0.3 μM.
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Validations
Human CD147 / EMMPRIN / Basigin Protein SDS-PAGE
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