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Product Name
Human ASGPR1 (His Tag) recombinant protein
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Description
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
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Protein name
Asialoglycoprotein receptor 1
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Protein short names
CLEC4H1; RP23-172M21.2; ASGPR; ASGR1; ASGPR1; HS.12056; HL-1; ASGR; ASGR-1
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Uniprot ID
P07306
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Gene Name
ASGR1; CLEC4H1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ASGR1 isoform 1 (P07306) (Gln 62-Leu 291) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ASGR1 consists of 246 amino acids and has a calculated molecular mass of 28.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhASGR1 is approximately 37 kDa due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
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