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Product Name
Anti-XRCC1 Rabbit antibody
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Description
XRCC1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human XRCC1
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/2000
IHC: 1/50-1/200
ICC/IF: 1/50-1/200
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Validations
Western blot analysis of XRCC1 expression in HeLa cell lysate.
Immunohistochemical analysis of paraffin-embedded human testis, using XRCC1 Antibody.
Immunofluorescent analysis of Hela cells, using XRCC1 Antibody .
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Background
Swiss-Prot Acc.P18887.XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins. At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK, DNA ligase III, poly (ADP-ribose) polymerase, and PCNA.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"