Anti-XRCC1 Rabbit antibody

Cat.#: 167578

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Product Information

  • Product Name
    Anti-XRCC1 Rabbit antibody
  • Documents
  • Description
    XRCC1 Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human XRCC1
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/50

  • Validations

    Western blot detection of XRCC1 in A549,MCF-7,293T cell lysates using XRCC1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:82kDa.

    Western blot detection of XRCC1 in A549,MCF-7,293T cell lysates using XRCC1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:82kDa.

  • Background
    The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"