Anti-Ubiquitin (linkage-specific K63) Rabbit antibody

Cat.#: 167803

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Product Information

  • Product Name
    Anti-Ubiquitin (linkage-specific K63) Rabbit antibody
  • Documents
  • Description
    Ubiquitin (linkage-specific K63) Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Ubiquitin (linkage-specific K63)
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/100

    FC: 1/50

  • Validations

    Western blot detection of Ubiquitin (linkage-specific K63) in Hela,A549 cell lysates using Ubiquitin (linkage-specific K63) Rabbit mAb(1:1000 diluted).Predicted band size:8kDa.Observed band size:8kDa.

    Western blot detection of Ubiquitin (linkage-specific K63) in Hela,A549 cell lysates using Ubiquitin (linkage-specific K63) Rabbit mAb(1:1000 diluted).Predicted band size:8kDa.Observed band size:8kDa.

  • Background
    This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"