-
Product Name
Anti-SQSTM1/p62 (3F8) Mouse antibody
- Documents
-
Description
SQSTM1/p62 (3F8) Mouse monoclonal antibody
-
Tested applications
WB, IHC-P, FC
-
Species reactivity
Human
-
Isotype
Mouse IgG1
-
Preparation
Antigen: Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
-
Clonality
Monoclonal
-
Formulation
Purified antibody in PBS with 0.05% sodium azide
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
FC: 1/200 - 1/400
ELISA: 1/10000
-
Validations
Western blot analysis of extracts from Jurkat,A549,MCF7,C6 and Hela cell lysates using SQSTM1/p62 mouse mAb (1:1000 diluted).Predicted band size:62KDa.Observed band size:62KDa.
-
Background
Swiss-Prot Acc.Q13501.This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"