Anti-Phospho-Tau (Ser202) Rabbit antibody

Anti-Phospho-Tau (Ser202) Rabbit antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Phospho-Tau (Ser202) Rabbit monoclonal antibody

WB, IP

Human, Mouse, Rat

TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103 antibody

Rabbit IgG

Antigen: A synthetic phosphopeptide corresponding to residues surrounding Ser202 of human Tau

Monoclonal

Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.P10636.Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.