Anti-N Cadherin Rabbit antibody

Cat.#: 166908

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Product Information

  • Product Name
    Anti-N Cadherin Rabbit antibody
  • Documents
  • Description
    N Cadherin Rabbit polyclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    CDHN; NCAD; CD325; CDw325 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human N Cadherin
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of N Cadherin in HepG2 cell lysates using N Cadherin Rabbit pAb(1:1000 diluted).Predicted band size:100KDa.Observed band size:140KDa.

    Western blot detection of N Cadherin in HepG2 cell lysates using N Cadherin Rabbit pAb(1:1000 diluted).Predicted band size:100KDa.Observed band size:140KDa.

  • Background
    Swiss-Prot Acc.P19022.Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density .

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"