Anti-MonoMethyl-Histone H3 (Lys18) Rabbit antibody

Cat.#: 167743

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Product Information

  • Product Name
    Anti-MonoMethyl-Histone H3 (Lys18) Rabbit antibody
  • Documents
  • Description
    MonoMethyl-Histone H3 (Lys18) Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthesized peptide derived from human Histone H3 (mono methyl K18)
  • Clonality
    Monoclonal
  • Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500-1/2000

    IHC: 1/500-1/2000

    ICC/IF: 1/100-1/500

  • Validations

    Western blot detection of MonoMethyl-Histone H3 (Lys18) in Hela,A549,HL-60,U2OS,U87-MG cell lysates using MonoMethyl-Histone H3 (Lys18) Rabbit mAb(1:1000 diluted).Observed band size:15kDa.

    Western blot detection of MonoMethyl-Histone H3 (Lys18) in Hela,A549,HL-60,U2OS,U87-MG cell lysates using MonoMethyl-Histone H3 (Lys18) Rabbit mAb(1:1000 diluted).Observed band size:15kDa.

  • Background
    Swiss-Prot Acc.P68431.H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"