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Product Name
Anti-MMP2 Rabbit antibody
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Description
MMP2 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human MMP2
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:500~1:1000
1:50~1:200
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Validations
Immunohistochemical analysis of paraffin-embedded human breast adenocarcinoma, using MMP2 Antibody.
Western blot analysis of MMP2 expression in (1)L6 cell lysate;(2)HeLa cell lysate.
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Background
Swiss-Prot Acc.P08253.MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"