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Product Name
Anti-MK2 Rabbit antibody
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Description
MK2 Rabbit monoclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human, Mouse, Rat
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Isotype
IgG
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Preparation
Antigen: A synthetic peptide of human MK2
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
IP: 1/50
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Validations
Western blot detection of MK2 in HL-60,U2OS cell lysates using MK2 Rabbit mAb(1:1000 diluted).Predicted band size:46kDa.Observed band size:46kDa.
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Background
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"