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Product Name
Anti-IL-1RA Rabbit antibody
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Description
IL-1RA Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human IL1RA
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/5000
IHC: 1/50
ICC/IF: 1/100
FC: 1/20
IP: 1/20
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Validations
Western blot detection of IL-1RA in K562,3T3,Hela cell lysates using IL-1RA Rabbit pAb(1:1000 diluted).Predicted band size:20kDa.Observed band size:20kDa.
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Background
Swiss-Prot Acc.P18510.Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"