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Product Name
Anti-FOXO1 Rabbit antibody
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Description
FOXO1 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human FoxO1a
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/2000
IHC: 1/50-1/200
ICC/IF: 1/50-1/200
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Validations
Immunohistochemical analysis of paraffin-embedded human brain carcinoma, using FoxO1a Antibody.
Immunofluorescent analysis of Hela cells, using FoxO1a Antibody .
Western blot detection of FoxO1a in Jurkat, THP-1, SKOV-3, MCF7 and Hela cell lysates using FoxO1a rabbit pAb (1:1000 diluted).Predicted band size:70kDa.Observed band size:78 to 82kDa.
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Background
Swiss-Prot Acc.Q12778.Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"