Anti-FGFR3 Rabbit antibody

Cat.#: 167925

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Special Price 247.7 USD

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Product Information

  • Product Name
    Anti-FGFR3 Rabbit antibody
  • Documents
  • Description
    FGFR3 Rabbit monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human FGFR3
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of FGFR3 in Hela,A549,HL-60,U2OS,C6 cell lysates using FGFR3 Rabbit mAb(1:1000 diluted).Predicted band size:88kDa.Observed band size:125kDa.

    Western blot detection of FGFR3 in Hela,A549,HL-60,U2OS,C6 cell lysates using FGFR3 Rabbit mAb(1:1000 diluted).Predicted band size:88kDa.Observed band size:125kDa.

  • Background
    This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"