Cart 2

Anti-eIF4EBP1 Rabbit antibody

Cat.#: 166664

Size:

Special Price 116.1 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-eIF4EBP1 Rabbit antibody
  • Documents
  • Description
    eIF4EBP1 Rabbit polyclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    4E-BP1; 4EBP1; 4EBP1_HUMAN; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1. antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Synthetic peptide.
  • Clonality
    Polyclonal
  • Formulation
    Purified Rabbit polyclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Immunoprecipitation analysis of Hela cell lysates using 4E-BP1 Rabbit pAb.

    Immunoprecipitation analysis of Hela cell lysates using 4E-BP1 Rabbit pAb.

    Western blot detection of 4E-BP1 in SHSY-5Y, C2C12 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

    Western blot detection of 4E-BP1 in SHSY-5Y, C2C12 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

    Western blot detection of 4E-BP1 in C2C12, A549 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

    Western blot detection of 4E-BP1 in C2C12, A549 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

    Western blot detection of 4E-BP1 in Jurkat, Hela and C6 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

    Western blot detection of 4E-BP1 in Jurkat, Hela and C6 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

  • Background
    Swiss-Prot Acc.Q13541.4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"