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Product Name
Anti-eIF4A1 Rabbit antibody
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Description
eIF4A1 Rabbit polyclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human eIF4A1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IP: 1/20
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Validations
Western blot detection of eIF4A1 in K562,C6,3T3,Hela cell lysates using eIF4A1 Rabbit pAb(1:1000 diluted).Predicted band size:46kDa.Observed band size:46kDa.
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Background
Swiss-Prot Acc.P60842.ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"