Anti-Cytochrome C (7C10) Mouse antibody

Cat.#: 168101

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Product Information

  • Product Name
    Anti-Cytochrome C (7C10) Mouse antibody
  • Documents
  • Description
    Cytochrome C (7C10) Mouse monoclonal antibody
  • Tested applications
    WB, ICC/IF, IHC-P
  • Species reactivity
    Human, Mouse, Rat, Chicken
  • Isotype
    IgG1
  • Preparation
    Antigen: Recombinant Protein of CYCS
  • Clonality
    Monoclonal
  • Formulation
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000-5000

    IHC: 1/500-1000

    IF: 1/200

  • Validations

    Western blot detection of Cytochrome c in T47D,3T3,COS7,C6 and Hela cell lysates using Cytochrome c mouse mAb (1:10000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

    Western blot detection of Cytochrome c in T47D,3T3,COS7,C6 and Hela cell lysates using Cytochrome c mouse mAb (1:10000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

  • Background
    Swiss-Prot Acc.P99999.Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SitesFeature keyPosition(s)Description
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"