Anti-Cytochrome C Rabbit antibody

Cat.#: 167414

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Cytochrome C Rabbit antibody
  • Documents
  • Description
    Cytochrome C Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CYC; HCS; THC4 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Cytochrome C
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    ICC/IF: 1/20-1/50

    IP: 1/20

  • Validations

    Western blot detection of Cytochrome C in K562,Rat Brain,C6,3T3,Hela cell lysates using Cytochrome C Rabbit pAb(1:1000 diluted).Predicted band size:12kDa.Observed band size:14kDa.

    Western blot detection of Cytochrome C in K562,Rat Brain,C6,3T3,Hela cell lysates using Cytochrome C Rabbit pAb(1:1000 diluted).Predicted band size:12kDa.Observed band size:14kDa.

  • Background
    Swiss-Prot Acc.P99999.Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SitesFeature keyPosition(s)Description
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"