Anti-Caldesmon/CDM Rabbit antibody

Cat.#: 167779

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Product Information

  • Product Name
    Anti-Caldesmon/CDM Rabbit antibody
  • Documents
  • Description
    Caldesmon/CDM Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Caldesmon/CDM
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/20

  • Validations

    Western blot detection of Caldesmon/CDM in Hela,C6 cell lysates using Caldesmon/CDM Rabbit mAb(1:1000 diluted).Predicted band size:93kDa.Observed band size:80kDa.

    Western blot detection of Caldesmon/CDM in Hela,C6 cell lysates using Caldesmon/CDM Rabbit mAb(1:1000 diluted).Predicted band size:93kDa.Observed band size:80kDa.

  • Background
    This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"