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Product Name
Anti-Bcl10 Rabbit antibody
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Description
Bcl10 Rabbit monoclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human
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Alternative names
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Bcl10
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000-1:5000
1:50-1:200
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Validations
Western blot detection of Bcl10 in K562,C6,3T3,Hela cell lysates using Bcl10 Rabbit mAb(1:1000 diluted).Predicted band size:26kDa.Observed band size:26kDa.
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Background
Swiss-Prot Acc.O95999.Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"