-
Product Name
Anti-APPL Rabbit antibody
- Documents
-
Description
APPL Rabbit polyclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
APPL; MODY14; DIP13alpha antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human APPL
-
Clonality
Polyclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
-
Applications
WB: 1/1000-1/5000
IHC: 1/20
ICC/IF: 1/50
-
Validations
Western blot detection of APPL in Rat Brain,C6,3T3,Hela cell lysates using APPL Rabbit pAb(1:1000 diluted).Predicted band size:80kDa.Observed band size:80kDa.
Immunohistochemistry of APPL in paraffin-embedded Human lung cancer tissue using APPL Rabbit pAb at dilution 1/20
-
Background
Swiss-Prot Acc.Q9UKG1.Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"