WDR1 Polyclonal Antibody

Cat.#: 166045

Special Price 290.3 USD

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Product Information

  • Product Name
    WDR1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to WDR1
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    WDR1 antibody; AIP1 antibody; HEL-S-52 antibody; NORI-1 antibody; WD repeat domain 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic Peptide of human WDR1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
  • Validations

    Western blot - WDR1 Polyclonal Antibody

    Western blot - WDR1 Polyclonal Antibody

    Western blot analysis of extracts of CEM cells, using WDR1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"