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Product Name
Vixarelimab reference antibody
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Description
Anti-OSMR Antibody (Vixarelimab)
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Tested applications
ELISA
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Species reactivity
Human OSMR
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Isotype
IgG4SP
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Preparation
Recombinant expression and purified from CHO cells.
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Clonality
Monoclonal
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Formulation
0.1 M Pro-Ac, 20 mM Arg, pH 5.0
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Storage instructions
-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
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Validations
SDS-PAGE
Anti-OSMR Antibody (vixarelimab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of Anti-OSMR Antibody (vixarelimab) is 96.9%, determined by SEC-HPLC.
Bioactivity: ELISA
Immobilized human OSMR His at 2 ug/mL can bind Anti-OSMR Antibody (vixarelimab), EC50=0.0024 ug/mL.
Bioactivity: FACS
Human OSMR HEK293 cells were stained with Anti-OSMR Antibody (vixarelimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.0359 ug/mL.
Function: Phosphorylation
Anti-OSMR Antibody (vixarelimab) P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.
Function: MCP-1 Secretion
Anti-OSMR Antibody (vixarelimab). MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"