Vixarelimab reference antibody

Cat.#: 176984

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Product Information

  • Product Name
    Vixarelimab reference antibody
  • Documents
  • Description
    Anti-OSMR Antibody (Vixarelimab)
  • Tested applications
    ELISA
  • Species reactivity
    Human OSMR
  • Isotype
    IgG4SP
  • Preparation
    Recombinant expression and purified from CHO cells.
  • Clonality
    Monoclonal
  • Formulation
    0.1 M Pro-Ac, 20 mM Arg, pH 5.0
  • Storage instructions
    -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
  • Validations

    SDS-PAGE

    SDS-PAGE

    Anti-OSMR Antibody (vixarelimab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

    SEC-HPLC

    SEC-HPLC

    The purity of Anti-OSMR Antibody (vixarelimab) is 96.9%, determined by SEC-HPLC.

    Bioactivity: ELISA

    Bioactivity: ELISA

    Immobilized human OSMR His at 2 ug/mL can bind Anti-OSMR Antibody (vixarelimab), EC50=0.0024 ug/mL.

    Bioactivity: FACS

    Bioactivity: FACS

    Human OSMR HEK293 cells were stained with Anti-OSMR Antibody (vixarelimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.0359 ug/mL.

    Function: Phosphorylation

    Function: Phosphorylation

    Anti-OSMR Antibody (vixarelimab) P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.

    Function: MCP-1 Secretion

    Function: MCP-1 Secretion

    Anti-OSMR Antibody (vixarelimab). MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"