VIPAS39 Polyclonal Antibody

Cat.#: 164126

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Product Information

  • Product Name
    VIPAS39 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to VIPAS39
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    VIPAS39 antibody; C14orf133 antibody; SPE-39 antibody; SPE39 antibody; VIPAR antibody; VPS16B antibody; hSPE-39 antibody; spermatogenesis-defective protein 39 homolog antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human VIPAS39 (NP_071350.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - VIPAS39 Polyclonal Antibody

    Western blot - VIPAS39 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using VIPAS39 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 15s.

  • Background
    Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"