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Product Name
Human C14orf133 Recombinant protein (His tag)
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Description
Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity). {UniProtKB:Q23288, PubMed:19109425, PubMed:20190753}.
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Protein name
Spermatogenesis-defective protein 39 homolog
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Protein short names
C14orf133; SPE39; VIPAR
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Uniprot ID
Q9H9C1
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Gene Name
VIPAS39; C14orf133; SPE39; VIPAR
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human VIPAS39 (NP_001180243.1) 147-493 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human C14orf133 SDS-PAGE
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