VEGF Receptor 2 antibody

VEGF Receptor 2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

VEGF Receptor 2 Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue, mouse heart tissue. Positive IHC detected in human oesophagus cancer tissue, human colon cancer tissue, human lung cancer tissue. Observed molecular weight by Western-blot: 200 kDa

ELISA, IHC, WB

Human, Mouse; other species not tested.

CD309 antibody; Fetal liver kinase 1 antibody; FLK 1 antibody; FLK1 antibody; KDR antibody; Kinase insert domain receptor antibody; VEGF Receptor 2 antibody; VEGFR antibody; VEGFR 2 antibody; VEGFR2 antibody

Rabbit IgG

This antibody was obtained by immunization of VEGF Receptor 2 recombinant protein (Accession Number: NM_002253). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.