VAMP2 antibody

VAMP2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

VAMP2 Rabbit Polyclonal antibody. Positive IHC detected in human skeletal muscle tissue. Positive WB detected in mouse brain tissue, fetal human brain tissue. Observed molecular weight by Western-blot: 19 kDa

ELISA, IHC, WB

Human,Mouse,Rat; other species not tested.

FLJ11460 antibody; SYB2 antibody; Synaptobrevin 2 antibody; VAMP 2 antibody; VAMP2 antibody

Rabbit IgG

This antibody was obtained by immunization of VAMP2 recombinant protein (Accession Number: NM_014232). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

VAMP2 (vesicle-associated membrane protein 2), also named as synaptobrevin 2, is a member of the SNARE (soluble NSF-attachment protein receptor) family of proteins. Characterized by a common sequence called the SNARE motif, SNARE proteins are involved in membrane fusion and vesicular transport (PMID: 11252968). VAMP2 consists of a short N-terminal sequence, a SNARE motif, and a C-terminal transmembrane region. It is required for fast calcium-triggered synaptic vesicle fusion. VAMP2 forms a stable complex with STX1 (syntaxin 1) and SNAP25 (synaptosomal-associated protein 25) during synaptic vesicle fusion (PMID: 16793874). It also forms a distinct complex with synaptophysin. VAMP2 is expressed in nervous system and some non-neuronal tissues, such as skeletal muscle (PMID: 18570252).