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Product Name
Human UBE2D1 (His Tag) recombinant protein
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Description
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
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Protein name
Ubiquitin-conjugating enzyme E2 D1
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Protein short names
UBCH5A; SFT; E2(17)KB1; UBC4/5; UBCH5; MGC28550; UBE2D1
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Uniprot ID
P51668
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Gene Name
UBE2D1; SFT; UBC5A; UBCH5; UBCH5A
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human UBE2D1 consisting of 161 amino acids and has a calculated molecular mass of 18.3 kDa. It migrates as an approximately16 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human UBE2D1 / UBCH5 Protein (His Tag) SDS-PAGE
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