Product Name

UBAC1 antibody

Documents

Description

UBAC1 Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue. Positive WB detected in human brain tissue, human heart tissue, mouse brain tissue, mouse heart tissue, rat liver tissue. Observed molecular weight by Western-blot: 46 kDa

Tested applications

ELISA, WB, IHC

Species reactivity

Human,Mouse,Rat; other species not tested.

Alternative names

GBDR1 antibody; KPC2 antibody; RP11 432J22.3 antibody; UBA domain containing 1 antibody; UBAC1 antibody; UBADC1 antibody

Immunogen

Human UBAC1 Recombinant protein (GST tag)

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of UBAC1 recombinant protein (Accession Number: NM_016172). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

WB: 1:1000-1:10000

IHC: 1:20-1:200

Validations

human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116471(UBAC1 antibody) at dilution of 1:500

Immunohistochemical of paraffin-embedded human heart using Catalog No:116471(UBAC1 antibody) at dilution of 1:100 (under 10x lens)

Immunohistochemical of paraffin-embedded human heart using Catalog No:116471(UBAC1 antibody) at dilution of 1:100 (under 40x lens)

Background

UBAC1(Ubiquitin-associated domain-containing protein 1) is also named as GBDR1, KPC2, UBADC1.It has several putative phosphorylation sites, including 8 CK2 (see 115440) sites, as well as 1 N-glycosylation site and 2 N-myristoylation sites(PMID:10857748).It is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.Northern blot analysis shows UBAC1 expression with the highest levels in heart and skeletal muscle and lowest level in lung.This antibody is specific to UBAC1.

UBAC1 antibody

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