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Product Name
TXNRD3 antibody
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Description
TXNRD3 Rabbit Polyclonal antibody. Positive WB detected in human testis tissue. Positive IHC detected in human testis. Observed molecular weight by Western-blot: 82kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human; other species not tested.
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Alternative names
TXNRD3 antibody; TR2 antibody; Thioredoxin reductase TR2 antibody; thioredoxin reductase 3 antibody; TRXR3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: XM_001130163). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:116460(TXNRD3 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human testis using Catalog No:116460(TXNRD3 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human testis using Catalog No:116460(TXNRD3 antibody) at dilution of 1:50 (under 40x lens)
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Background
TXNRD3, also named as TGR and TRXR3, belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. TXNRD3 displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. TXNRD3 catalyzes the reaction: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. TXNRD3 promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"