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Product Name
Mouse XEDAR/EDA2R (Fc Tag) recombinant protein
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Description
Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6 (By similarity).
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Protein name
Tumor necrosis factor receptor superfamily member 27
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Protein short names
9430060M22RIK; RP23-188N15.1; EDAA2R; EDA-A2R; TNFRSF27; XEDAR; MGC124099; EDA2R; UNQ2448/PRO5727/PRO34080
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Uniprot ID
Q8BX35
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Gene Name
Eda2r; Tnfrsf27; Xedar
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse EDA2R (Q8BX35) (Met1-Thr138) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse EDA2R /Fc is a disulfide-linked homodimer. The reduced monomer comprises 379 amino acids and has a predicted molecular mass of 42.4 kDa. The apparent molecular mass of the protein is approximately 49 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse XEDAR / EDA2R Protein (Fc Tag) SDS-PAGE
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