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Product Name
Human XEDAR/EDA2R (His Tag) recombinant protein
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Description
Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
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Protein name
Tumor necrosis factor receptor superfamily member 27
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Protein short names
9430060M22RIK; RP23-188N15.1; EDAA2R; XEDAR; EDA-A2R; TNFRSF27; MGC124099; EDA2R; UNQ2448/PRO5727/PRO34080
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Uniprot ID
Q9HAV5
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Gene Name
EDA2R; TNFRSF27; XEDAR; UNQ2448/PRO5727/PRO34080
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human EDA2R (NP_068555.1) extracellular domain (Met 1-Thr 138) fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human EDA2R consists of 149 amino acids and predictes a molecular mass of 16.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEDA2R is approximately 33 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human XEDAR / EDA2R Protein (His Tag) SDS-PAGE
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