-
Product Name
Human GITR / TNFRSF18 (Fc Tag) recombinant protein
- Documents
-
Description
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
-
Protein name
Tumor necrosis factor receptor superfamily member 18
-
Protein short names
CD357; RP5-902P8.2; GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN; ACTIVATION-INDUCIBLE TNFR FAMILY RECEPTOR; GITR-D; TNF RECEPTOR SUPERFAMILY ACTIVATION-INDUCIBLE PROTEIN; GITR; RP23-118E21.6; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18; AITR
-
Uniprot ID
Q9Y5U5
-
Gene Name
TNFRSF18; AITR; GITR; UNQ319/PRO364
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human TNFRSF18 (Q9Y5U5-1) (Met1-Glu161) was expressed with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human TNFRSF18/Fc is a disulfide-linked homodimer. The reduced monomer comprises 377 amino acids and has a predicted molecular mass of 41.5 kDa. The apparent molecular mass of the protein is approximately 96 and 45 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 90 % as determined by SDS-PAGE
-
Validations
Human GITR / TNFRSF18 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"