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Product Name
Mouse TNFSF12 (Fc Tag) recombinant protein
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Description
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity).
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Protein name
Tumor necrosis factor ligand superfamily member 12
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Protein short names
DR3LG; RP23-422L16.25-001; TNF-RELATED WEAK INDUCER OF APOPTOSIS; APO3 LIGAND; APO3/DR3 LIGAND; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12; DR3L; UNQ181/PRO207; TUMOR NECROSIS FACTOR (LIGAND) SUPERFAMILY; MEMBER 12; TWEAK; APO3L; TNFSF12
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Uniprot ID
Q5F2A0
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Gene Name
Tnfsf12
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Tnfsf12 (NP_035744.1) (Arg105-His249) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Tnfsf12 consists 405 amino acids and predicts a molecular mass of 44.4 kDa.
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Purity
> (83.8+3.6) % as determined by SDS-PAGE.
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Validations
Tnfsf12 protein SDS-PAGE
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