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Product Name
TSN antibody
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Description
TSN Rabbit Polyclonal antibody. Positive IP detected in MCF-7 cells. Positive WB detected in Jurkat cells, HeLa cells, MCF-7 cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 26 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
REHF 1 antibody; translin antibody; TRSLN antibody; TSN antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004622). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116436(TSN Antibody) at dilution of 1:600
IP Result of anti-TSN (IP:Catalog No:116436, 3ug; Detection:Catalog No:116436 1:300) with MCF-7 cells lysate 1600ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:116436(TSN Antibody) at dilution of 1:50 (under 40x lens)
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Background
TSN, also named as Translin or Component 3 of promoter of RISC, is a 228 amino acid protein, which belongs to the translin family. TSN as a DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translations, mostly is involved in immunoglobulin T-cell receptor gene segments. TSN May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"