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Product Name
Human TPM4 / tropomyosin 4 (His Tag) recombinant protein
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Description
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
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Protein name
Tropomyosin alpha-4 chain
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Protein short names
TROPOMYOSIN 4; 2610528G24RIK; TROPOMYOSIN ALPHA-4 CHAIN; TM30P1; TPM4
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Uniprot ID
P67936
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Gene Name
TPM4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TPM4 (P67936) (Ala2-Ile248) was expressed with an N-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human TPM4 comprises 267 amino acids and has a predicted molecular mass of 30.8 kDa. The apparent molecular mass of the protein is approximately 35-40 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human TPM4 / Tropomyosin 4 Protein (His Tag) SDS-PAGE
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