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Product Name
Human TPM1 / Tropomyosin-1 (His Tag) recombinant protein
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Description
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
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Protein name
Tropomyosin alpha-1 chain
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Protein short names
TROPOMYOSIN 1 (ALPHA) ISOFORM 6; TROPOMYOSIN 1 (ALPHA) ISOFORM 4; TPM-1; CMH3; HYPERTROPHIC 3; TROPOMYOSIN 1 (ALPHA) ISOFORM 3; TROPOMYOSIN-1; TPM1; TROPOMYOSIN 1; TMPA; TM2; AA986836; C15ORF13; TMSA; TM3; TROPOMYOSIN 1 (ALPHA) ISOFORM 1; ALPHA TROPOMYOSIN; ALPHA-TROPOMYOSIN; AI854628; LVNC9; TROPOMYOSIN ALPHA-1 CHAIN; SARCOMERIC TROPOMYOSIN KAPPA; CARDIOMYOPATHY; CMD1Y; ALPHA-TM; TROPOMYOSIN 1 (ALPHA) ISOFORM 5; TROPOMYOSIN 1 (ALPHA); TROPOMYOSIN 1 (ALPHA) ISOFORM 7; ALPHA; TROPOMYOSIN 1 (ALPHA) ISOFORM 2; HTM-ALPHA
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Uniprot ID
P09493
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Gene Name
TPM1; C15orf13; TMSA
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TPM1 (NP_000357.3) (Met1-Met284) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TPM1 consists of 299 amino acids and predicts a molecular mass of 34.7 KDa. It migrates as an approximately 35 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human TPM1 / Tropomyosin-1 Protein (His Tag) SDS-PAGE
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