Human TPM1/C15orf13/TMSA (His tag) recombinant protein

Cat.#: 518494

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Product Information

  • Product Name
    Human TPM1/C15orf13/TMSA (His tag) recombinant protein
  • Documents
  • Description
    Tropomyosin α-1 Chain (TPM1) is a member of the Tropomyosin family of highly conserved and widely distributed Actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 binds to Actin filaments in both muscle and non-muscle cells. It is one type of α-helical chain that forms the predominant Tropomyosin of striated muscle. TPM1 plays a central role in association with the Troponin complex and the Calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with Caldesmon. In non-muscle cells, it is implicated in stabilizing the cytoskeleton Actin filaments. Defects in TPM1 are associated with type 3 Familial Hypertrophic Cardiomyopathy.
  • Protein name
    tropomyosin 1 (alpha)(TPM1)
  • Protein short names
    C15orf13; TMSA
  • Uniprot ID
    P09493
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TPM1/C15orf13/TMSA Met1-Met284 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TPM1/C15orf13/TMSA (His tag) recombinant protein

    Human TPM1/C15orf13/TMSA (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"